Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MITF | O75030 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.49 |
| ▸ | CBFB | Q13951 | 1/20 | 0.49 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4556802 | 0.83 | CHRM2 (0.39) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL2913073 | 0.82 | CHRM2 (0.55) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL29711228 | 0.82 | CHRM2 (0.55) | MAPTMEN1KMT2ALMNAKDM4E | |
| Hydrochloric Acid SCHEMBL2913065 | 0.81 | CHRM2 (0.54) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL2914961 | 0.80 | CHRM2 (0.53) | MAPTMEN1KMT2ALMNAKDM4E | |
| Hydrochloric Acid SCHEMBL2921746 | 0.79 | CHRM2 (0.52) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL2912554 | 0.78 | CHRM2 (0.73) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL31447589 | 0.78 | CHRM2 (0.73) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL4447690 | 0.78 | CHRM2 (0.51) | MAPTMEN1KMT2ALMNAKDM4E | |
| Hydrochloric Acid SCHEMBL2923090 | 0.77 | CHRM2 (0.72) | MAPTMEN1KMT2ALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622478-B2 | 1-nitroacridine/tumor inhibitor compositions | TIWARI RAJ | 2009-11-24 | — | — | US | claimed |