Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 14/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 14/20 | 0.36 |
| ▸ | ITGB7 | P26010 | 12/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | ITGAV | P06756 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4203929 | 0.85 | ITGB1 (0.35) | ITGB1ITGA4ITGB7CCR2 | |
| SCHEMBL4566698 | 0.85 | ITGB1 (0.35) | ITGB1ITGA4ITGB7 | |
| SCHEMBL4458135 | 0.85 | ITGB1 (0.38) | ITGB1ITGA4ITGB7ITGAV | |
| SCHEMBL2770139 | 0.79 | ITGB1 (0.56) | ITGB1ITGA4ITGB7ITGAV | |
| SCHEMBL4564578 | 0.77 | ITGB1 (0.40) | ITGB1ITGA4ITGB7ITGAV | |
| SCHEMBL4206085 | 0.76 | ITGB1 (0.35) | ITGB1ITGA4ITGB7 | |
| SCHEMBL4451903 | 0.75 | ITGB1 (0.36) | ITGB1ITGA4ITGB7ITGAV | |
| SCHEMBL4457975 | 0.75 | ITGB1 (0.39) | ITGB1ITGA4ITGB7ITGAV | |
| SCHEMBL4453759 | 0.74 | ITGB1 (0.41) | ITGB1ITGA4ITGB7ITGAV | |
| SCHEMBL4195563 | 0.74 | ITGB1 (0.35) | ITGB1ITGA4ITGB7ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1635822-A4 | METHODS AND COMPOSITIONS FOR TREATING RHEUMATOID ARTHRITIS | ELAN PHARM INC (US) | 2009-06-24 | — | — | EP | disclosed |
| EP-1635822-A2 | METHODS AND COMPOSITIONS FOR TREATING RHEUMATOID ARTHRITIS | Elan Pharmaceuticals, Inc. (US) | 2006-03-22 | — | — | EP | disclosed |
| WO-2005000246-A2 | METHODS AND COMPOSITIONS FOR TREATING RHEUMATOID ARTHRITIS | ELAN PHARMACEUTICALS, INC. (US) | 2005-01-06 | — | — | WO | disclosed |