Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1977460 | 0.95 | IDH1 (0.77) | IDH1HSD11B1 | |
| SCHEMBL2007243 | 0.94 | IDH1 (0.88) | IDH1HSD11B1 | |
| SCHEMBL4557076 | 0.94 | IDH1 (0.68) | IDH1HSD11B1 | |
| SCHEMBL4452120 | 0.86 | IDH1 (0.86) | IDH1HSD11B1 | |
| SCHEMBL1977464 | 0.85 | IDH1 (0.61) | IDH1HSD11B1 | |
| SCHEMBL13182605 | 0.84 | IDH1 (0.92) | IDH1HSD11B1 | |
| SCHEMBL1975070 | 0.84 | IDH1 (0.92) | IDH1HSD11B1 | |
| SCHEMBL1968317 | 0.84 | IDH1 (0.85) | IDH1HSD11B1 | |
| SCHEMBL2006015 | 0.83 | IDH1 (0.65) | IDH1HSD11B1 | |
| SCHEMBL13271533 | 0.83 | IDH1 (0.65) | IDH1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2086939-A2 | PYRIDINE CARBOXAMIDES AS 11-BETA-HSD1 INHIBITORS | AstraZeneca AB (SE) | 2009-08-12 | — | — | EP | disclosed |
| WO-2008053194-A2 | PYRIDINE CARBOXAMIDES AS 11-BETA-HSD1 INHIBITORS | ASTRAZENECA AB (SE) | 2008-05-08 | — | — | WO | disclosed |