Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 19/20 | 0.73 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.53 |
| ▸ | MGLL | Q99685 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4557128 | 1.00 | HRH3 (0.73) | HRH3KCNH2MGLL | |
| Fumaric Acid SCHEMBL1814555 | 0.94 | HRH3 (0.66) | HRH3KCNH2MGLL | |
| SCHEMBL12655843 | 0.88 | HRH3 (0.74) | HRH3KCNH2MGLL | |
| SCHEMBL1812862 | 0.85 | HRH3 (0.71) | HRH3KCNH2 | |
| SCHEMBL1811575 | 0.84 | HRH3 (1.00) | HRH3KCNH2 | |
| SCHEMBL1810769 | 0.83 | HRH3 (0.98) | HRH3KCNH2 | |
| SCHEMBL1811411 | 0.83 | HRH3 (0.98) | HRH3KCNH2 | |
| SCHEMBL1812849 | 0.83 | HRH3 (0.85) | HRH3KCNH2 | |
| SCHEMBL1808914 | 0.83 | HRH3 (0.85) | HRH3KCNH2 | |
| SCHEMBL1811732 | 0.82 | HRH3 (0.66) | HRH3KCNH2MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074088-A2 | N-SUBSTITUTED-AZACYCLYLAMINES AS HISTAMINE-3 ANTAGONISTS | Wyeth (US) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008045371-A2 | N-SUBSTITUTED-AZACYCLYLAMINES AS HISTAMINE-3 ANTAGONISTS | WYETH (US) | 2008-04-17 | — | — | WO | disclosed |