Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 2/20 | 0.32 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.32 |
| ▸ | ATP1A1 | P05023 | 2/20 | 0.31 |
| ▸ | ATP1B1 | P05026 | 2/20 | 0.31 |
| ▸ | ATP1A3 | P13637 | 2/20 | 0.31 |
| ▸ | ATP1B2 | P14415 | 2/20 | 0.31 |
| ▸ | ATP1A2 | P50993 | 2/20 | 0.31 |
| ▸ | ATP1B3 | P54709 | 2/20 | 0.31 |
| ▸ | FXYD2 | P54710 | 2/20 | 0.31 |
| ▸ | ATP1A4 | Q13733 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8996745 | 0.89 | SRD5A1 (0.34) | SRD5A1SRD5A2 | |
| SCHEMBL8996742 | 0.89 | SRD5A1 (0.34) | SRD5A1SRD5A2 | |
| SCHEMBL8523198 | 0.86 | SRD5A1 (0.34) | SRD5A1SRD5A2 | |
| SCHEMBL8579148 | 0.84 | SRD5A1 (0.41) | SRD5A1SRD5A2 | |
| SCHEMBL8996758 | 0.82 | SRD5A1 (0.36) | SRD5A1SRD5A2ATP1A1ATP1B1ATP1A3 | |
| SCHEMBL8996766 | 0.82 | SRD5A1 (0.36) | SRD5A1SRD5A2ATP1A1ATP1B1ATP1A3 | |
| SCHEMBL8524687 | 0.82 | SRD5A1 (0.34) | SRD5A1SRD5A2 | |
| SCHEMBL8524586 | 0.80 | CDK5 (0.35) | SRD5A1SRD5A2ATP1A1ATP1B1ATP1A3 | |
| SCHEMBL8524175 | 0.79 | SRD5A1 (0.36) | SRD5A1SRD5A2 | |
| SCHEMBL8996714 | 0.78 | SRD5A1 (0.34) | SRD5A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1865955-A4 | METHOD OF TREATING MEN WITH TESTOSTERONE SUPPLEMENT AND 5ALPHA-REDUCTASE INHIBITOR | MERCK & CO INC (US) | 2009-04-15 | — | — | EP | disclosed |
| EP-1865955-A2 | METHOD OF TREATING MEN WITH TESTOSTERONE SUPPLEMENT AND 5ALPHA-REDUCTASE INHIBITOR | Merck & Co., Inc. (US) | 2007-12-19 | — | — | EP | disclosed |
| WO-2006104762-A2 | METHOD OF TREATING MEN WITH TESTOSTERONE SUPPLEMENT AND 5ALPHA-REDUCTASE INHIBITOR | MERCK & CO., INC. (US) | 2006-10-05 | — | — | WO | disclosed |