Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPFFR1 | Q9GZQ6 | 5/20 | 0.57 |
| ▸ | NPFFR2 | Q9Y5X5 | 5/20 | 0.57 |
| ▸ | TNFRSF1A | P19438 | 3/20 | 0.43 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4331994 | 1.00 | NPFFR1 (0.57) | NPFFR1NPFFR2TNFRSF1ASLC9A1SMN1; SMN2 | |
| SCHEMBL4456172 | 0.82 | NPFFR1 (0.36) | NPFFR1NPFFR2SMN1; SMN2LMNAKDM4E | |
| SCHEMBL4451545 | 0.81 | PTPN1 (0.50) | SMN1; SMN2LMNAKDM4EMAPTALDH1A1 | |
| SCHEMBL4330988 | 0.79 | NPFFR1 (0.53) | NPFFR1NPFFR2TNFRSF1ASLC9A1LMNA | |
| SCHEMBL4331989 | 0.74 | MAPT (0.57) | NPFFR1NPFFR2SMN1; SMN2LMNAKDM4E | |
| SCHEMBL4331998 | 0.74 | MAPT (0.57) | NPFFR1NPFFR2SMN1; SMN2LMNAKDM4E | |
| SCHEMBL4331560 | 0.72 | NPFFR1 (0.66) | NPFFR1NPFFR2SMN1; SMN2LMNAKDM4E | |
| SCHEMBL4331556 | 0.72 | NPFFR1 (0.66) | NPFFR1NPFFR2SMN1; SMN2LMNAKDM4E | |
| SCHEMBL4336070 | 0.72 | KDM4E (0.47) | NPFFR1NPFFR2SLC9A1SMN1; SMN2LMNA | |
| SCHEMBL4336074 | 0.72 | KDM4E (0.47) | NPFFR1NPFFR2SLC9A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521062-B2 | Thiosemicarbazones as anti-virals and immunopotentiators | NOVARTIS VACCINES & DIAGNOSTICS, INC. (US) | 2009-04-21 | — | — | US | disclosed |