SCHEMBL4557536

SCHEMBL4557536

O=C(NCCOCCOCCOCCOCCOCCOCCOCCOCCO)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.59

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.59
EPHX2 P34913 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
LMNA P02545 1/20 0.48
FABP7 O15540 1/20 0.41
FABP5 Q01469 1/20 0.41
CASP3 P42574 2/20 0.41
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30094166 1.00 KMT2A (0.59) KMT2AEPHX2SMN1; SMN2LMNAFABP7
SCHEMBL30094147 1.00 KMT2A (0.59) KMT2AEPHX2SMN1; SMN2LMNAFABP7
SCHEMBL4556421 1.00 KMT2A (0.59) KMT2AEPHX2SMN1; SMN2LMNAFABP7
SCHEMBL19050989 1.00 KMT2A (0.59) KMT2AEPHX2SMN1; SMN2LMNAFABP7
SCHEMBL31548843 1.00 KMT2A (0.59) KMT2AEPHX2SMN1; SMN2LMNAFABP7
SCHEMBL20173568 1.00 KMT2A (0.59) KMT2AEPHX2SMN1; SMN2LMNAFABP7
SCHEMBL13671094 1.00 KMT2A (0.59) KMT2AEPHX2SMN1; SMN2LMNAFABP7
SCHEMBL4557033 1.00 KMT2A (0.59) KMT2AEPHX2SMN1; SMN2LMNAFABP7
SCHEMBL1782935 0.99 KMT2A (0.60) KMT2AEPHX2SMN1; SMN2LMNAFABP7
SCHEMBL31010196 0.93 KMT2A (0.60) KMT2AEPHX2SMN1; SMN2LMNAFABP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7598421-B2 Materials for the delivery of biologically-active material to cells UCL BIOMEDICA PLC (GB) 2009-10-06 US disclosed
US-7598421-B2 Materials for the delivery of biologically-active material to cells UCL BIOMEDICA PLC (GB) 2009-10-06 US disclosed
WO-2005117985-A2 LIPOPOLYPLEX CONSTRUCT WITH AN INTEGRIN BINDING PEPTIDE FOR DELIVERY OF NUCLEIC ACIDS, PEPTIDES OR DRUGS UCL BIOMEDICA PLC (GB) 2005-12-15 WO disclosed
US-20050245446-A1 Materials for the delivery of biologically-active material to cells NANOGENICS LIMITED (GB) 2005-11-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050245446-A1 Materials for the delivery of biologically-active material to cells ITGB1, ITGA2B, ITGB2 KMT2A 4254/4885EPHX2 2782/4885SMN1; SMN2 2326/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.