SCHEMBL455830

SCHEMBL455830

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nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.39
SLCO1B1 Q9Y6L6 1/20 0.39
PDE4A P27815 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2718998 0.91 USP2 (0.39) USP2SLCO1B1PDE4A
SCHEMBL2558949 0.88 USP2 (0.39) USP2SLCO1B1PDE4A
SCHEMBL3642844 0.88 USP2 (0.39) USP2SLCO1B1PDE4A
SCHEMBL17201985 0.86 USP2 (0.42) USP2SLCO1B1PDE4A
SCHEMBL2346239 0.84 USP2 (0.36) USP2SLCO1B1
SCHEMBL2723086 0.81 USP2 (0.38) USP2SLCO1B1
SCHEMBL11041165 0.76 USP2 (0.39) USP2SLCO1B1PDE4A
SCHEMBL3628255 0.76 USP2 (0.39) USP2SLCO1B1PDE4A
SCHEMBL3230568 0.76 USP2 (0.39) USP2SLCO1B1PDE4A
SCHEMBL3227090 0.76 USP2 (0.39) USP2SLCO1B1PDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1809758-A4 IN VIVO SITE-SPECIFIC INCORPORATION OF N-ACETYL-GALACTOSAMINE AMINO ACIDS IN EUBACTERIA SCRIPPS RESEARCH INST (US) 2009-04-01 EP claimed
EP-1809758-A2 IN VIVO SITE-SPECIFIC INCORPORATION OF N-ACETYL-GALACTOSAMINE AMINO ACIDS IN EUBACTERIA The Scripps Research Institute (US) 2007-07-25 EP claimed
WO-2006045116-A2 IN VIVO SITE-SPECIFIC INCORPORATION OF N-ACETYL-GALACTOSAMINE AMINO ACIDS IN EUBACTERIA THE SCRIPPS RESEARCH INSTITUTE (US) 2006-04-27 WO claimed
WO-2024077277-A1 DRUG LINKERS AND ANTIBODY CONJUGATES THEREOF AMBRX, INC. (US) 2024-04-11 WO disclosed
CN-105793241-B Terpyridyl complex compound and its purposes in electrochromic applications based on metal 耶达研究及发展有限公司 2019-06-18 CN disclosed
EP-2968552-A1 TARGETING AGENT ANTIBODY CONJUGATES AND USES THEREOF The California Institute for Biomedical Research (US) 2016-01-20 EP disclosed
WO-2014153164-A1 TARGETING AGENT ANTIBODY CONJUGATES AND USES THEREOF THE CALIFORNIA INSTITUTE FOR BIOMEDICAL RESEARCH (US) 2014-09-25 WO disclosed
EP-2640745-A2 ANTIBODY DERIVATIVES Allozyne, Inc. (US) 2013-09-25 EP disclosed
WO-2012032181-A9 ANTIBODY DERIVATIVES ALLOZYNE, INC (US) 2013-06-13 WO disclosed
WO-2012032181-A2 NOVEL ANTIBODY DERIVATIVES ALLOZYNE, INC (US) 2012-03-15 WO disclosed
EP-1809758-A4 IN VIVO SITE-SPECIFIC INCORPORATION OF N-ACETYL-GALACTOSAMINE AMINO ACIDS IN EUBACTERIA SCRIPPS RESEARCH INST (US) 2009-04-01 EP disclosed
EP-1809758-A2 IN VIVO SITE-SPECIFIC INCORPORATION OF N-ACETYL-GALACTOSAMINE AMINO ACIDS IN EUBACTERIA The Scripps Research Institute (US) 2007-07-25 EP disclosed
WO-2006045116-A2 IN VIVO SITE-SPECIFIC INCORPORATION OF N-ACETYL-GALACTOSAMINE AMINO ACIDS IN EUBACTERIA THE SCRIPPS RESEARCH INSTITUTE (US) 2006-04-27 WO disclosed