Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 20/20 | 0.65 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.60 |
| ▸ | FABP1 | P07148 | 7/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | FABP4 | P15090 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2006338 | 0.89 | NR1H4 (0.72) | NR1H4HSD17B13FABP1CYP1A2CYP2C9 | |
| SCHEMBL2003218 | 0.87 | NR1H4 (0.72) | NR1H4HSD17B13FABP1CYP1A2CYP2C9 | |
| SCHEMBL2001897 | 0.85 | NR1H4 (0.74) | NR1H4HSD17B13FABP1CYP1A2CYP2C9 | |
| SCHEMBL4340030 | 0.85 | NR1H4 (0.67) | NR1H4HSD17B13FABP1CYP1A2CYP2C9 | |
| SCHEMBL2001904 | 0.82 | NR1H4 (0.62) | NR1H4HSD17B13FABP1CYP1A2CYP2C9 | |
| SCHEMBL1998428 | 0.82 | NR1H4 (0.66) | NR1H4HSD17B13FABP1CYP1A2CYP2C9 | |
| SCHEMBL13335357 | 0.82 | NR1H4 (0.71) | NR1H4HSD17B13FABP1FABP4 | |
| SCHEMBL2000305 | 0.81 | NR1H4 (0.62) | NR1H4HSD17B13FABP1CYP1A2CYP2C9 | |
| SCHEMBL23474151 | 0.79 | NR1H4 (0.63) | NR1H4HSD17B13FABP1FABP4 | |
| SCHEMBL4340034 | 0.79 | NR1H4 (0.59) | NR1H4HSD17B13FABP1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079307-A2 | FARNESOID X RECEPTOR AGONISTS | SmithKline Beecham Corporation (US) | 2009-07-22 | — | — | EP | disclosed |
| WO-2008051942-A2 | FARNESOID X RECEPTOR AGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-05-02 | — | — | WO | disclosed |