Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4336029 | 1.00 | PDE4B (0.89) | PDE4BPDE5A | |
| SCHEMBL4349536 | 1.00 | PDE4B (0.89) | PDE4BPDE5A | |
| SCHEMBL4338000 | 0.94 | PDE4B (0.80) | PDE4BPDE5A | |
| SCHEMBL583180 | 0.94 | PDE4B (1.00) | PDE4B | |
| SCHEMBL582697 | 0.89 | PDE4B (0.92) | PDE4BPDE5A | |
| SCHEMBL4334216 | 0.88 | PDE4B (0.73) | PDE4B | |
| SCHEMBL5963176 | 0.87 | PDE4B (0.88) | PDE4B | |
| SCHEMBL583169 | 0.87 | PDE4B (1.00) | PDE4BPDE5A | |
| SCHEMBL2774197 | 0.86 | PDE4B (1.00) | PDE4B | |
| SCHEMBL583691 | 0.86 | PDE4B (1.00) | PDE4BPDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539753-A2 | PYRAZOLO(3,4-B)PYRIDINE COMPOUNDS, AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2005-06-15 | — | — | EP | claimed |
| WO-2004024728-A2 | PYRAZOLO[3,4-B]PYRIDINE COMPOUNDS, AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2004-03-25 | — | — | WO | claimed |
| EP-1539753-B1 | PYRAZOLO(3,4-B)PYRIDINE COMPOUNDS, AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | GLAXO GROUP LTD (GB) | 2009-09-09 | — | — | EP | disclosed |