SCHEMBL4558896

SCHEMBL4558896

CCCCCC(=O)CCC(=O)CCCCC

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.71
MAPT P10636 1/20 0.71
CES2 O00748 4/20 0.63
CES1 P23141 4/20 0.63
AKR1B1 P15121 1/20 0.60
GPR84 Q9NQS5 7/20 0.57
PPARG P37231 7/20 0.57
PPARD Q03181 7/20 0.57
PPARA Q07869 7/20 0.57
HDAC11 Q96DB2 5/20 0.57
TSHR P16473 4/20 0.57
PTPN1 P18031 3/20 0.57
ALDH1A1 P00352 2/20 0.57
TLR2 O60603 2/20 0.57
TDP1 Q9NUW8 2/20 0.57
FABP4 P15090 2/20 0.57
SLC22A6 Q4U2R8 1/20 0.57
SLC22A8 Q8TCC7 1/20 0.57
MEN1 O00255 1/20 0.57
ESR1 P03372 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29030206 0.97 KMT2A (0.76) KMT2AMAPTCES2CES1GPR84
SCHEMBL12503965 0.97 KMT2A (0.76) KMT2AMAPTCES2CES1GPR84
SCHEMBL11683635 0.97 KMT2A (0.76) KMT2AMAPTCES2CES1GPR84
SCHEMBL11335702 0.97 KMT2A (0.76) KMT2AMAPTCES2CES1GPR84
SCHEMBL10866088 0.97 KMT2A (0.76) KMT2AMAPTCES2CES1GPR84
SCHEMBL23735964 0.97 KMT2A (0.68) KMT2AMAPTCES2CES1AKR1B1
SCHEMBL9628746 0.97 KMT2A (0.76) KMT2AMAPTCES2CES1GPR84
SCHEMBL8193983 0.97 KMT2A (0.76) KMT2AMAPTCES2CES1GPR84
SCHEMBL9628655 0.97 KMT2A (0.76) KMT2AMAPTCES2CES1GPR84
SCHEMBL10744476 0.97 KMT2A (0.76) KMT2AMAPTCES2CES1GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9194471-A None JP disclosed
EP-4006063-A1 METHOD FOR PRODUCING FLUOROPOLYMER, POLYTETRAFLUOROETHYLENE COMPOSITION, AND POLYTETRAFLUOROETHYLENE POWDER Daikin Industries, Ltd. (JP) 2022-06-01 EP disclosed
EP-3922435-A1 COMPOSITION, STRETCHED BODY AND METHOD OF MANUFACTURING THEREOF DAIKIN INDUSTRIES, LTD. (JP) 2021-12-15 EP disclosed
EP-3919527-A1 METHOD FOR PRODUCING POLYTETRAFLUOROETHYLENE DAIKIN INDUSTRIES, LTD. (JP) 2021-12-08 EP disclosed
EP-3862324-A1 METHOD FOR REMOVING FLUORINE-CONTAINING COMPOUND FROM WASTE WATER DAIKIN INDUSTRIES, LTD. (JP) 2021-08-11 EP disclosed
EP-3862368-A1 POLYTETRAFLUOROETHYLENE PRODUCTION METHOD DAIKIN INDUSTRIES, LTD. (JP) 2021-08-11 EP disclosed
EP-3666802-A1 METHOD FOR PRODUCING PURIFIED POLYTETRAFLUOROETHYLENE AQUEOUS DISPERSION LIQUID, METHOD FOR PRODUCING MODIFIED POLYTETRAFLUOROETHYLENE POWDER, METHOD FOR PRODUCING POLYTETRAFLUOROETHYLENE MOLDED BODY, AND COMPOSITION Daikin Industries, Ltd. (JP) 2020-06-17 EP disclosed
US-7488832-B2 e.g. N-[amino(imino)methyl]-2-[2-(4-phenoxyphenyl)-5-phenyl-1H-pyrrol-1-yl]acetamide; beta -amyloid deposits and neurofibrillary tangles; cognition activator, neurodegenerative diseases; Alzheimer's disease, Down's syndrome WYETH (US) 2009-02-10 US disclosed
US-20080287424-A1 AZOLYLACYLGUANIDINES AS beta-SECRETASE INHIBITORS WYETH (US) 2008-11-20 US disclosed
US-20060183790-A1 Azolylacylguanidines as beta-secretase inhibitors WYETH (US) 2006-08-17 US disclosed
JP-H09194471-A 2,5-DIARYLFURAN DERIVATIVE AND ITS PRODUCTION MITSUBISHI CHEM CORP 1997-07-29 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080287424-A1 AZOLYLACYLGUANIDINES AS beta-SECRETASE INHIBITORS BACE1, BACE2, APP KMT2A 634/4885MAPT 30/4885CES2 2049/4885
US-20060183790-A1 Azolylacylguanidines as beta-secretase inhibitors BACE1, BACE2, APP KMT2A 634/4885MAPT 30/4885CES2 2049/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.