Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 5/20 | 0.41 |
| ▸ | CA1 | P00915 | 5/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | CA9 | Q16790 | 4/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | CKS1B | P61024 | 1/20 | 0.39 |
| ▸ | SKP1 | P63208 | 1/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL631279 | 0.80 | TDP1 (0.46) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL12482641 | 0.80 | TDP1 (0.56) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL3250569 | 0.79 | TDP1 (0.45) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL13055395 | 0.78 | TDP1 (0.55) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL1979026 | 0.78 | TDP1 (0.55) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL11346435 | 0.77 | CA12 (0.50) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL14568632 | 0.77 | TDP1 (0.50) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL3341020 | 0.77 | TDP1 (0.67) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL2747817 | 0.77 | TDP1 (0.53) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL479811 | 0.77 | TDP1 (0.53) | TDP1MEN1GAAKMT2AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044128-A2 | NOVEL AMPHIPHILIC CYCLODEXTRIN DERIVATIVES | Centre National De La Recherche Scientifique-CNRS (FR) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008009831-A2 | NOVEL AMPHIPHILIC CYCLODEXTRIN DERIVATIVES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS (FR) | 2008-01-24 | — | — | WO | disclosed |