Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F9 | P00740 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 5/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | DBH | P09172 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21776830 | 0.82 | NOTUM (0.52) | NOTUM | |
| SCHEMBL19402280 | 0.76 | NOTUM (0.47) | NOTUMCYP3A4CYP2C9ALDH1A1SMN1; SMN2 | |
| SCHEMBL17188088 | 0.75 | MYC (0.50) | F9NOTUMALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL5477117 | 0.74 | NOTUM (0.52) | NOTUMCYP3A4CYP2C9ALDH1A1TSHR | |
| SCHEMBL2215697 | 0.72 | NOTUM (0.49) | NOTUMTTRALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL4886069 | 0.72 | MAPT (0.47) | NOTUMHSD17B10ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL12263160 | 0.71 | NOTUM (0.55) | NOTUMTTRSMN1; SMN2MAPT | |
| SCHEMBL20096920 | 0.70 | NOTUM (0.50) | NOTUMALDH1A1SMN1; SMN2NPC1MAPT | |
| SCHEMBL2211673 | 0.68 | NOTUM (0.54) | NOTUMALDH1A1CYP1A2CYP2C19NPC1 | |
| SCHEMBL23975942 | 0.68 | NOTUM (0.52) | F9NOTUMCYP3A4CYP2C9SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090318429-A1 | Compounds, Compositions and Methods Comprising Heteroaromatic Derivatives | INSTITUTE FOR ONEWORLD HEALTH | 2009-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318429-A1 | Compounds, Compositions and Methods Comprising Heteroaromatic Derivatives | CFTR, PKD1, PKD2 | F9 2601/4885NOTUM 3691/4885CYP3A4 1541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.