Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.58 |
| ▸ | CA2 | P00918 | 5/20 | 0.58 |
| ▸ | CA12 | O43570 | 3/20 | 0.58 |
| ▸ | CA9 | Q16790 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4558676 | 1.00 | CA1 (0.58) | CA1CA2CA12CA9HSD17B10 | |
| SCHEMBL4560269 | 1.00 | CA1 (0.58) | CA1CA2CA12CA9HSD17B10 | |
| SCHEMBL4560693 | 1.00 | CA1 (0.58) | CA1CA2CA12CA9HSD17B10 | |
| SCHEMBL4558461 | 1.00 | CA1 (0.58) | CA1CA2CA12CA9HSD17B10 | |
| SCHEMBL4560295 | 1.00 | CA1 (0.58) | CA1CA2CA12CA9HSD17B10 | |
| SCHEMBL4559836 | 1.00 | CA1 (0.58) | CA1CA2CA12CA9HSD17B10 | |
| SCHEMBL4559957 | 1.00 | CA1 (0.58) | CA1CA2CA12CA9HSD17B10 | |
| SCHEMBL4560947 | 1.00 | CA1 (0.58) | CA1CA2CA12CA9HSD17B10 | |
| SCHEMBL4560750 | 1.00 | CA1 (0.58) | CA1CA2CA12CA9HSD17B10 | |
| SCHEMBL4560260 | 1.00 | CA1 (0.58) | CA1CA2CA12CA9HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090123516-A1 | DRUG DELIVERY FROM IMPLANTS USING SELF-ASSEMBLED MONOLAYERS-THERAPEUTIC SAMS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2009-05-14 | — | — | US | disclosed |