SCHEMBL4560415

SCHEMBL4560415

Nc1[nH]c(=O)[nH]c(=O)c1N.Nc1[nH]c(=O)[nH]c(=O)c1N

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYMP P19971 7/20 0.56
PNP P00491 1/20 0.56
GDA Q9Y2T3 1/20 0.38
G6PD P11413 1/20 0.37
GAA P10253 1/20 0.36
ALDH1A1 P00352 3/20 0.36
MAPT P10636 2/20 0.36
RPS6KA3 P51812 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
KDM4E B2RXH2 1/20 0.31
CA12 O43570 1/20 0.31
PARP1 P09874 1/20 0.31
CA9 Q16790 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1099736 1.00 TYMP (0.56) TYMPPNPGDAG6PDGAA
Hydrochloric Acid SCHEMBL5026974 0.97 TYMP (0.58) TYMPPNPGDAG6PDGAA
Sulfuric Acid SCHEMBL1872872 0.88 TYMP (0.46) TYMPPNPGDAG6PDGAA
Sulfurous Acid SCHEMBL29541185 0.88 TYMP (0.46) TYMPPNPGDAG6PDGAA
Sulfuric Acid SCHEMBL28938055 0.88 TYMP (0.46) TYMPPNPGDAG6PDGAA
SCHEMBL12265283 0.77
SCHEMBL2891526 0.72 TYMP (0.52) TYMPPNPGDAALDH1A1RPS6KA3
SCHEMBL1228773 0.72 TYMP (1.00) TYMPPNPGDAG6PDGAA
SCHEMBL4560430 0.72 TYMP (1.00) TYMPPNPMAPT
SCHEMBL4560171 0.72 TYMP (0.52) TYMPPNPGDAALDH1A1RPS6KA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7557175-B2 Poly(carbonate-co-urea) copolymers and melt transesterification method of preparing these copolymers SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-07-07 US disclosed