Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 8/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 8/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 8/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 8/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 8/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 8/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4560127 | 1.00 | HSD17B10 (0.48) | HSD17B10CYP2C9ALDH1A1HPGDALOX15 | |
| SCHEMBL4559806 | 1.00 | HSD17B10 (0.48) | HSD17B10CYP2C9ALDH1A1HPGDALOX15 | |
| SCHEMBL4560642 | 1.00 | HSD17B10 (0.48) | HSD17B10CYP2C9ALDH1A1HPGDALOX15 | |
| SCHEMBL4558417 | 1.00 | HSD17B10 (0.48) | HSD17B10CYP2C9ALDH1A1HPGDALOX15 | |
| SCHEMBL4558437 | 1.00 | HSD17B10 (0.48) | HSD17B10CYP2C9ALDH1A1HPGDALOX15 | |
| SCHEMBL4560879 | 1.00 | HSD17B10 (0.48) | HSD17B10CYP2C9ALDH1A1HPGDALOX15 | |
| SCHEMBL4560254 | 1.00 | HSD17B10 (0.48) | HSD17B10CYP2C9ALDH1A1HPGDALOX15 | |
| SCHEMBL4560306 | 1.00 | HSD17B10 (0.48) | HSD17B10CYP2C9ALDH1A1HPGDALOX15 | |
| SCHEMBL4559804 | 1.00 | HSD17B10 (0.48) | HSD17B10CYP2C9ALDH1A1HPGDALOX15 | |
| SCHEMBL4559857 | 1.00 | HSD17B10 (0.48) | HSD17B10CYP2C9ALDH1A1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090123516-A1 | DRUG DELIVERY FROM IMPLANTS USING SELF-ASSEMBLED MONOLAYERS-THERAPEUTIC SAMS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2009-05-14 | — | — | US | disclosed |