Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4562073 | 0.81 | HCRTR1 (0.66) | HCRTR1HCRTR2 | |
| SCHEMBL15238454 | 0.81 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL27928874 | 0.79 | HCRTR1 (0.68) | HCRTR1HCRTR2 | |
| SCHEMBL4560858 | 0.77 | HCRTR1 (0.67) | HCRTR1HCRTR2 | |
| SCHEMBL4539499 | 0.76 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL27911310 | 0.76 | HCRTR1 (0.68) | HCRTR1HCRTR2 | |
| SCHEMBL4534129 | 0.67 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL4541421 | 0.65 | HCRTR2 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL15238307 | 0.65 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL4536645 | 0.65 | HCRTR1 (0.73) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2638008-A1 | LACTAM DERIVATIVES USEFUL AS OREXIN RECEPTOR ANTAGONISTS | Actelion Pharmaceuticals Ltd. (CH) | 2013-09-18 | — | — | EP | disclosed |
| WO-2012063207-A1 | LACTAM DERIVATIVES USEFUL AS OREXIN RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2012-05-18 | — | — | WO | disclosed |