Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4538458 | 0.90 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL4536704 | 0.86 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL4541940 | 0.84 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL15238290 | 0.81 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL4538298 | 0.81 | HCRTR2 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL4540613 | 0.80 | HCRTR1 (0.79) | HCRTR1HCRTR2 | |
| SCHEMBL4561667 | 0.79 | HCRTR2 (0.72) | HCRTR1HCRTR2 | |
| SCHEMBL4542479 | 0.79 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL4535731 | 0.77 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL4532405 | 0.77 | HCRTR1 (1.00) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2638008-A1 | LACTAM DERIVATIVES USEFUL AS OREXIN RECEPTOR ANTAGONISTS | Actelion Pharmaceuticals Ltd. (CH) | 2013-09-18 | — | — | EP | disclosed |
| WO-2012063207-A1 | LACTAM DERIVATIVES USEFUL AS OREXIN RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2012-05-18 | — | — | WO | disclosed |