Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.42 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 3/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14759636 | 1.00 | LPAR2 (0.42) | LPAR2LPAR3LPAR1FAAHTRPV1 | |
| SCHEMBL2724494 | 1.00 | LPAR2 (0.42) | LPAR2LPAR3LPAR1FAAHTRPV1 | |
| SCHEMBL15209157 | 1.00 | LPAR2 (0.42) | LPAR2LPAR3LPAR1FAAHTRPV1 | |
| SCHEMBL15472172 | 1.00 | LPAR2 (0.42) | LPAR2LPAR3LPAR1FAAHTRPV1 | |
| SCHEMBL14889709 | 1.00 | LPAR2 (0.42) | LPAR2LPAR3LPAR1FAAHTRPV1 | |
| SCHEMBL14900455 | 1.00 | LPAR2 (0.42) | LPAR2LPAR3LPAR1FAAHTRPV1 | |
| SCHEMBL2724499 | 1.00 | LPAR2 (0.42) | LPAR2LPAR3LPAR1FAAHTRPV1 | |
| SCHEMBL15472141 | 1.00 | LPAR2 (0.42) | LPAR2LPAR3LPAR1FAAHTRPV1 | |
| SCHEMBL15472173 | 1.00 | LPAR2 (0.42) | LPAR2LPAR3LPAR1FAAHTRPV1 | |
| SCHEMBL2724728 | 1.00 | LPAR2 (0.42) | LPAR2LPAR3LPAR1FAAHTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012061259-A2 | NOVEL LOW MOLECULAR WEIGHT CYCLIC AMINE CONTAINING CATIONIC LIPIDS FOR OLIGONUCLEOTIDE DELIVERY | MERCK SHARP & DOHME CORP. (US) | 2012-05-10 | — | — | WO | disclosed |