⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27839166 | 0.95 | CA12 (0.58) | — | |
| SCHEMBL28247367 | 0.79 | CA12 (0.62) | — | |
| Carbon Dioxide SCHEMBL27984684 | 0.78 | CA12 (0.71) | — | |
| SCHEMBL4519512 | 0.77 | — | — | |
| SCHEMBL210457 | 0.74 | — | — | |
| SCHEMBL27944857 | 0.73 | — | — | |
| SCHEMBL2428440 | 0.73 | — | — | |
| SCHEMBL7060892 | 0.73 | CA12 (0.62) | — | |
| SCHEMBL1046393 | 0.73 | — | — | |
| SCHEMBL1140581 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 299 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012078637-A2 | COMPOSITION AND METHOD FOR OLIGONUCLEOTIDE DELIVERY | IMMUNE DISEASE INSTITUTE, INC. (US) | 2012-06-14 | — | — | WO | claimed |
| US-7479536-B1 | Chiral, charged peptide nucleic acid oligomers from cyclic monomers | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2009-01-20 | — | — | US | claimed |
| WO-1998010786-A2 | PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF SYNDROME X OF REAVEN | COHEN YAROM (IL) | 1998-03-19 | — | — | WO | claimed |
| US-5250517-A | Hypotensive and cardiotonic agents; cardiac insufficiency | HOFFMANN-LA ROCHE INC. (US) | 1993-10-05 | — | — | US | claimed |
| EP-0001449-B1 | ANALOGUES OF SOMATOSTATIN, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR PREPARATION | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1981-04-15 | — | — | EP | claimed |
| US-4145337-A | SOMATOSTATINS, ANTISECRETORY | HOFFMANN-LA ROCHE INC. (US) | 1979-03-20 | — | — | US | claimed |
| US-12018260-B2 | Tunable Reversir™ compounds | ALNYLAM PHARMACEUTICALS, INC. (US) | 2024-06-25 | — | — | US | disclosed |
| US-20240200061-A1 | TRANSTHYRETIN (TTR) iRNA COMPOSITIONS AND METHODS OF USE THEREOF FOR TREATING OR PREVENTING TTR-ASSOCIATED OCULAR DISEASES | ALNYLAM PHARMACEUTICALS, INC. | 2024-06-20 | — | — | US | disclosed |
| US-12005074-B2 | Extrahepatic delivery | ALNYLAM PHARMACEUTICALS, INC. (US) | 2024-06-11 | — | — | US | disclosed |
| US-20240175028-A1 | DOSING OF siRNA COMPOUNDS TO THE CISTERNA MAGNA | ALNYLAM PHARMACEUTICALS, INC (US) | 2024-05-30 | — | — | US | disclosed |
| EP-4373937-A1 | METABOLIC DISORDER-ASSOCIATED TARGET GENE IRNA COMPOSITIONS AND METHODS OF USE THEREOF | Alnylam Pharmaceuticals, Inc. (US) | 2024-05-29 | — | — | EP | disclosed |
| EP-4367237-A2 | BIS-RNAI COMPOUNDS FOR CNS DELIVERY | Alnylam Pharmaceuticals, Inc. (US) | 2024-05-15 | — | — | EP | disclosed |
| US-11976318-B2 | Compositions and methods for analyte detection | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2024-05-07 | — | — | US | disclosed |
| WO-1992020702-A1 | PEPTIDE NUCLEIC ACIDS | BUCHARDT OLE (DK) | 1992-11-26 | — | — | WO | disclosed |
| EP-0384362-A2 | Glycinderivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1990-08-29 | — | — | EP | disclosed |
| EP-0010297-B1 | DERIVATIVES OF POLYENE MACROLIDE ANTIBIOTICS CONTAINING AN AMINO SUGAR MOIETY, PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING CORPORATION (US) | 1983-04-13 | — | — | EP | disclosed |
| US-4272525-A | FUNGICIDES | SCHERING CORPORATION (US) | 1981-06-09 | — | — | US | disclosed |
| EP-0010297-A1 | Derivatives of polyene macrolide antibiotics containing an amino sugar moiety, process for the preparation thereof, and pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1980-04-30 | — | — | EP | disclosed |
| US-4145337-A | SOMATOSTATINS, ANTISECRETORY | HOFFMANN-LA ROCHE INC. (US) | 1979-03-20 | — | — | US | disclosed |
| US-4145337-A | SOMATOSTATINS, ANTISECRETORY | HOFFMANN-LA ROCHE INC. (US) | 1979-03-20 | — | — | US | disclosed |