Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 6/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 6/20 | 0.32 |
| ▸ | ITGB7 | P26010 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4448681 | 0.92 | — | — | |
| SCHEMBL4958912 | 0.88 | NPY2R (0.34) | ITGB1ITGA4ITGB7 | |
| SCHEMBL4421319 | 0.87 | ITGB1 (0.32) | ITGB1ITGA4ITGB7 | |
| SCHEMBL5615538 | 0.85 | ITGB1 (0.33) | ITGB1ITGA4ITGB7 | |
| SCHEMBL5609494 | 0.82 | — | — | |
| SCHEMBL3848898 | 0.81 | ITGB1 (0.38) | ITGB1ITGA4ITGB7 | |
| SCHEMBL4455497 | 0.80 | — | — | |
| SCHEMBL4449503 | 0.80 | ITGB1 (0.30) | ITGB1ITGA4 | |
| SCHEMBL4419699 | 0.79 | — | — | |
| SCHEMBL4422941 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592387-A4 | COMPOSITION FOR AND TREATMENT OF DEMYELINATING DISEASES AND PARALYSIS BY ADMINISTRATION OF REMYELINATING AGENTS | ELAN PHARM INC (US) | 2009-05-06 | — | — | EP | disclosed |
| EP-1592387-A2 | COMPOSITION FOR AND TREATMENT OF DEMYELINATING DISEASES AND PARALYSIS BY ADMINISTRATION OF REMYELINATING AGENTS | Elan Pharmaceuticals, Inc. (US) | 2005-11-09 | — | — | EP | disclosed |
| WO-2004066932-A2 | COMPOSITION FOR AND TREATMENT OF DEMYELINATING DISEASES AND PARALYSIS BY ADMINISTRATION OF REMYELINATING AGENTS | ELAN PHARMACEUTICALS INC. (US) | 2004-08-12 | — | — | WO | disclosed |