Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 13/20 | 0.51 |
| ▸ | FYN | P06241 | 5/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL469994 | 0.92 | FYN (0.47) | TTKFYNPIM1 | |
| SCHEMBL470169 | 0.92 | TTK (0.45) | TTKFYN | |
| SCHEMBL456811 | 0.86 | TTK (0.53) | TTKFYNPIM1ERN1 | |
| SCHEMBL457290 | 0.86 | TTK (0.43) | TTKPIM1ERN1 | |
| SCHEMBL459313 | 0.86 | TTK (0.47) | TTKERN1 | |
| SCHEMBL456263 | 0.85 | TTK (0.45) | TTKFYN | |
| SCHEMBL458258 | 0.81 | TTK (0.51) | TTKFYNPIM1 | |
| SCHEMBL454908 | 0.80 | TTK (0.63) | TTK | |
| SCHEMBL12466960 | 0.80 | TTK (0.79) | TTK | |
| SCHEMBL469926 | 0.79 | TTK (0.41) | TTKFYNPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614063-B1 | SUBSTITUTED IMIDAZOPYRIDAZINES | BAYER IP GMBH (DE) | 2016-01-13 | — | — | EP | disclosed |
| EP-2614063-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | Bayer Intellectual Property GmbH (DE) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012032031-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-03-15 | — | — | WO | disclosed |