SCHEMBL4562644

SCHEMBL4562644

CC[C@H]1O[C@@H]2SC(N(C)C)=NC2C(O)C1O

nearest known ligand 0.78

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
OGA O60502 19/20 0.78
HEXB P07686 4/20 0.76
HOGA1 Q86XE5 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4562643 1.00 OGA (0.78) OGAHEXBHOGA1
SCHEMBL4536649 1.00 OGA (0.78) OGAHEXBHOGA1
SCHEMBL5020873 0.88 OGA (0.82) OGAHEXBHOGA1
SCHEMBL15364757 0.88 OGA (0.82) OGAHEXBHOGA1
SCHEMBL4538051 0.88 OGA (0.82) OGAHEXBHOGA1
SCHEMBL5020485 0.88 OGA (0.74) OGAHEXBHOGA1
SCHEMBL14359898 0.88 OGA (1.00) OGAHEXBHOGA1
SCHEMBL4559749 0.88 OGA (1.00) OGAHEXBHOGA1
SCHEMBL1899664 0.88 OGA (1.00) OGAHEXBHOGA1
SCHEMBL14362101 0.88 OGA (1.00) OGAHEXBHOGA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2637503-A1 SELECTIVE GLYCOSIDASE INHIBITORS AND USES THEREOF Alectos Therapeutics Inc. (CA) 2013-09-18 EP disclosed
WO-2012064680-A1 SELECTIVE GLYCOSIDASE INHIBITORS AND USES THEREOF ALECTOS THERAPEUTICS INC. (CA) 2012-05-18 WO disclosed