Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 8/20 | 0.51 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.51 |
| ▸ | KDM5A | P29375 | 1/20 | 0.51 |
| ▸ | NSD2 | O96028 | 3/20 | 0.47 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.41 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4083519 | 0.88 | NSD2 (0.56) | KDM4CKDM5BKDM5ANSD2HSD11B1 | |
| SCHEMBL4085395 | 0.82 | MAPK14 (0.58) | KDM4CKDM5BKDM5ANSD2KDM2B | |
| SCHEMBL4085411 | 0.79 | KDM4C (0.57) | KDM4CKDM5BKDM5ANSD2TNIK | |
| SCHEMBL4084965 | 0.76 | KDM4C (0.61) | KDM4CKDM5BNSD2KDM2BHSD11B1 | |
| SCHEMBL19465343 | 0.72 | KDM5A (0.46) | KDM4CKDM5BKDM5AMAPK14TNIK | |
| SCHEMBL4913209 | 0.72 | NSD3 (0.66) | KDM4CKDM5BKDM5ANSD2KDM2B | |
| SCHEMBL18579664 | 0.72 | KDM4C (0.60) | KDM4CKDM5BKDM5AKDM2BMAPK14 | |
| SCHEMBL4795949 | 0.71 | TEK (0.65) | KDM4CKDM5BMAPK14 | |
| SCHEMBL15875369 | 0.70 | KDM5A (0.45) | KDM4CKDM5BKDM5ANSD2TGFBR1 | |
| SCHEMBL4058049 | 0.70 | CNR1 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2026798-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING CBX CANNABINOID RECEPTOR MODULATORS AND POTASSIUM CHANNEL MODULATORS | Solvay Pharmaceuticals GmbH (DE) | 2009-02-25 | — | — | EP | disclosed |
| WO-2007125048-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING CBX CANNABINOID RECEPTOR MODULATORS AND POTASSIUM CHANNEL MODULATORS | SOLVAY PHARMACEUTICALS GMBH (DE) | 2007-11-08 | — | — | WO | disclosed |