Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 20/20 | 0.68 |
| ▸ | BAK1 | Q16611 | 3/20 | 0.68 |
| ▸ | BCL2L1 | Q07817 | 17/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1743437 | 0.90 | BCL2 (0.71) | BCL2BAK1BCL2L1 | |
| SCHEMBL2990459 | 0.88 | BCL2 (0.79) | BCL2BAK1BCL2L1 | |
| SCHEMBL19424227 | 0.87 | BCL2 (0.65) | BCL2BAK1BCL2L1 | |
| SCHEMBL2987918 | 0.85 | BCL2 (0.74) | BCL2BAK1BCL2L1 | |
| SCHEMBL1744739 | 0.85 | BCL2 (0.67) | BCL2BAK1BCL2L1 | |
| SCHEMBL19425559 | 0.85 | BCL2 (0.62) | BCL2BAK1BCL2L1 | |
| SCHEMBL2990684 | 0.84 | BCL2 (0.75) | BCL2BAK1BCL2L1 | |
| SCHEMBL19425295 | 0.84 | BCL2L1 (0.66) | BCL2BAK1BCL2L1 | |
| SCHEMBL19425309 | 0.84 | BCL2 (0.70) | BCL2BAK1BCL2L1 | |
| SCHEMBL2996027 | 0.83 | BCL2 (0.74) | BCL2BAK1BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2061560-A2 | BCL INHIBITORS FOR TREATING PLATELET EXCESS | Abbott Laboratories (US) | 2009-05-27 | — | — | EP | disclosed |
| WO-2008030836-A2 | BCL INHIBITORS TREATING PLATELET EXCESS | ABBOTT LABORATORIES (US) | 2008-03-13 | — | — | WO | disclosed |