Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.45 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3988687 | 0.93 | KDM4E (0.57) | KDM4EPOLBGAAALDH1A1MEN1 | |
| SCHEMBL3984472 | 0.91 | KDM4E (0.55) | KDM4EPOLBGAAALDH1A1MEN1 | |
| SCHEMBL2704044 | 0.88 | POLB (0.62) | KDM4EPOLBGAAALDH1A1MEN1 | |
| SCHEMBL4797827 | 0.87 | KDM4E (0.53) | KDM4EPOLBGAAALDH1A1MEN1 | |
| SCHEMBL4797816 | 0.87 | KDM4E (0.53) | KDM4EPOLBGAAALDH1A1MEN1 | |
| SCHEMBL7892245 | 0.87 | KDM4E (0.59) | KDM4EPOLBGAAALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL4799421 | 0.86 | KDM4E (0.58) | KDM4EPOLBGAAALDH1A1MEN1 | |
| SCHEMBL4797829 | 0.85 | KDM4E (0.51) | KDM4EPOLBGAAALDH1A1MEN1 | |
| SCHEMBL4797824 | 0.85 | KDM4E (0.51) | KDM4EPOLBGAAALDH1A1MEN1 | |
| SCHEMBL4799736 | 0.83 | MIF (0.64) | KDM4EPOLBGAAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2124943-A1 | PYRAZOLO [3, 4-B]PYRIDINE DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008111009-A1 | PYRAZOLO [3, 4-B] PYRIDINE DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2008-09-18 | — | — | WO | disclosed |