Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 20/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.65 |
| ▸ | HRH1 | P35367 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3094821 | 0.99 | HRH3 (0.98) | HRH3KCNH2HRH1 | |
| SCHEMBL3089677 | 0.92 | HRH3 (0.86) | HRH3KCNH2HRH1 | |
| SCHEMBL3090975 | 0.89 | HRH3 (0.83) | HRH3HRH1 | |
| SCHEMBL3082047 | 0.88 | HRH3 (0.81) | HRH3HRH1 | |
| SCHEMBL1707159 | 0.88 | HRH3 (1.00) | HRH3HRH1 | |
| SCHEMBL3101097 | 0.87 | HRH3 (0.77) | HRH3HRH1 | |
| SCHEMBL14372315 | 0.87 | HRH3 (0.79) | HRH3HRH1 | |
| SCHEMBL3089554 | 0.86 | HRH3 (0.76) | HRH3 | |
| SCHEMBL3339325 | 0.86 | HRH3 (0.75) | HRH3HRH1 | |
| SCHEMBL3086198 | 0.86 | HRH3 (0.80) | HRH3HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2133340-B1 | Novel benzazepine derivatives | GLAXO GROUP LTD (GB) | 2013-01-16 | — | — | EP | claimed |
| EP-2133340-B1 | Novel benzazepine derivatives | GLAXO GROUP LTD (GB) | 2013-01-16 | — | — | EP | disclosed |
| EP-2133340-A1 | Novel benzazepine derivatives | Glaxo Group Limited (GB) | 2009-12-16 | — | — | EP | disclosed |