⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4024620 | 0.84 | — | — | |
| SCHEMBL5855547 | 0.78 | — | — | |
| SCHEMBL1566989 | 0.73 | — | — | |
| SCHEMBL7921744 | 0.73 | — | — | |
| Ethylene SCHEMBL248596 | 0.67 | — | — | |
| SCHEMBL8935714 | 0.67 | — | — | |
| SCHEMBL6887412 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL9677065 | 0.65 | — | — | |
| SCHEMBL3629399 | 0.65 | — | — | |
| SCHEMBL3722743 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117597133-A | Double stranded siRNA with patterned chemical modification | 阿塔兰塔治疗公司 | 2024-02-23 | — | — | CN | disclosed |
| WO-2021146488-A1 | 4'-O-METHYLENE PHOSPHONATE NUCLEIC ACIDS AND ANALOGUES THEREOF | DICERNA PHARMACEUTICALS, INC. (US) | 2021-07-22 | — | — | WO | disclosed |
| CN-108456227-B | A kind of chloro- 3- cyclobutenyl phosphonate compound of the fluoro- 3- sulfonyl -2- of 1,1- bis- and its synthetic method and application | 南京师范大学 | 2019-07-12 | — | — | CN | disclosed |
| CN-108383872-B | The fluoro- 3- sulfonyl -2,4- pentadiene phosphonate ester compound of one kind -1,1- two and its synthetic method and application | 南京师范大学 | 2019-07-12 | — | — | CN | disclosed |
| CN-106977545-B | A kind of 3- sweet-smelling formacyl difluoro methylene allyl phosphonic acid ester and its synthetic method | 南京师范大学 | 2019-04-12 | — | — | CN | disclosed |
| CN-108456227-A | A kind of chloro- 3- cyclobutenyls phosphonate compound of bis- fluoro- 3- sulfonyls -2- of 1,1- and its synthetic method and application | 南京师范大学 | 2018-08-28 | — | — | CN | disclosed |
| CN-108383872-A | Two fluoro- 3- sulfonyls -2,4- pentadienes phosphonate ester compounds of one kind -1,1- and its synthetic method and application | 南京师范大学 | 2018-08-10 | — | — | CN | disclosed |
| CN-105348321-B | One kind synthesis α, the method for α difluoro methylene alkenyl phosphonates | 南京师范大学 | 2017-10-10 | — | — | CN | disclosed |
| CN-105418685-B | A kind of synthetic method of six-membered cyclic difluoro methylene phosphonic lactone | 南京师范大学 | 2017-07-28 | — | — | CN | disclosed |
| CN-106977545-A | A kind of 3 sweet-smelling formacyl difluoro methylene allyl phosphonic acid esters and its synthetic method | 南京师范大学 | 2017-07-25 | — | — | CN | disclosed |
| US-7638637-B2 | Immunomodulators; amino-functional imidazole phosphonates and analogues thereof | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2009-12-29 | — | — | US | disclosed |
| US-20070088002-A1 | Orally available sphingosine 1-phosphate receptor agonists and antagonists | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-04-19 | — | — | US | disclosed |
| WO-2005041899-A2 | ORALLY AVAILABLE SPHINGOSINE 1-PHOSPHATE RECEPTOR AGONISTS AND ANTAGONISTS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2005-05-12 | — | — | WO | disclosed |
| WO-2003078443-A1 | PROCESSES FOR SYNTHESIS OF CYCLIC AND LINEAR POLYAMINE CHELATORS CONTAINING N-MONOSUBTITUTED COORDINATING ARMS | CHELATOR, LLC (US) | 2003-09-25 | — | — | WO | disclosed |
| US-6576760-B2 | Cyclization of a substituted polyamine having secondary amino groups by reaction with a bridging agent having two reactive groups each capable of nucleophilic attack by one of the secondary amine groups of the polyamine; chelate compound | CHELATOR LLC | 2003-06-10 | — | — | US | disclosed |
| US-20020091253-A1 | Processes for synthesis of cyclic and linear polyamine chelators containing N-monosubstituted coordinating arms | CONCAT, LTD. | 2002-07-11 | — | — | US | disclosed |