Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 20/20 | 0.69 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL602578 | 1.00 | HRH4 (0.69) | HRH4HRH3KCNH2 | |
| SCHEMBL602577 | 1.00 | HRH4 (0.69) | HRH4HRH3KCNH2 | |
| SCHEMBL602950 | 1.00 | HRH4 (0.69) | HRH4HRH3KCNH2 | |
| SCHEMBL603933 | 0.92 | HRH4 (0.57) | HRH4HRH3 | |
| SCHEMBL603932 | 0.92 | HRH4 (0.57) | HRH4HRH3 | |
| SCHEMBL604885 | 0.92 | HRH4 (0.57) | HRH4HRH3 | |
| SCHEMBL602515 | 0.82 | HRH4 (1.00) | HRH4HRH3 | |
| SCHEMBL601750 | 0.82 | HRH4 (1.00) | HRH4HRH3 | |
| SCHEMBL601749 | 0.82 | HRH4 (1.00) | HRH4HRH3 | |
| SCHEMBL602514 | 0.82 | HRH4 (1.00) | HRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009077608-A1 | 2 -AMINOPYRIMIDINE DERIVATIVES AS HISTAMINE H4 ANTAGONISTS | PALAU PHARMA, S. A. (ES) | 2009-06-25 | — | — | WO | claimed |
| WO-2009077608-A1 | 2 -AMINOPYRIMIDINE DERIVATIVES AS HISTAMINE H4 ANTAGONISTS | PALAU PHARMA, S. A. (ES) | 2009-06-25 | — | — | WO | disclosed |