SCHEMBL4563642

SCHEMBL4563642

CC(C)(C)Cc1nc2cc(S(=O)(=O)Nc3ccccc3)ccc2n1CC1CCOCC1

nearest known ligand 0.63

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 20/20 0.63
CNR1 P21554 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1609576 0.87 CNR2 (0.71) CNR2CNR1
SCHEMBL4004298 0.84 CNR2 (0.86) CNR2CNR1
SCHEMBL3998791 0.82 CNR2 (0.73) CNR2CNR1
SCHEMBL3999099 0.82 CNR2 (0.69) CNR2
SCHEMBL3998389 0.81 CNR2 (0.87) CNR2CNR1
SCHEMBL13606181 0.81 CNR2 (0.76) CNR2CNR1
SCHEMBL3997503 0.80 CNR2 (0.76) CNR2CNR1
SCHEMBL3998966 0.79 CNR2 (0.71) CNR2CNR1
SCHEMBL3998796 0.79 CNR2 (0.66) CNR2
SCHEMBL13605966 0.79 CNR2 (0.77) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2010526-A1 BENZIMIDAZOLE 5-SULFONAMIDE DERIVATIVES AS CANNABINOID 1 (CB1) RECEPTOR LIGANDS AstraZeneca AB (SE) 2009-01-07 EP claimed
WO-2007120101-A1 BENZIMIDAZOLE 5-SULFONAMIDE DERIVATIVES AS CANNABINOID 1 (CB1) RECEPTOR LIGANDS ASTRAZENECA AB (SE) 2007-10-25 WO claimed