Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 11/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4564010 | 1.00 | TAAR1 (0.56) | TAAR1 | |
| SCHEMBL2081578 | 0.94 | TAAR1 (0.65) | TAAR1 | |
| SCHEMBL2081587 | 0.94 | TAAR1 (0.65) | TAAR1 | |
| SCHEMBL2082099 | 0.73 | TAAR1 (0.61) | TAAR1 | |
| SCHEMBL2082102 | 0.73 | TAAR1 (0.61) | TAAR1 | |
| SCHEMBL2082026 | 0.72 | TAAR1 (1.00) | TAAR1 | |
| SCHEMBL2082029 | 0.72 | TAAR1 (1.00) | TAAR1 | |
| SCHEMBL2083198 | 0.71 | TAAR1 (0.68) | TAAR1 | |
| SCHEMBL2083197 | 0.71 | TAAR1 (0.68) | TAAR1 | |
| SCHEMBL2081702 | 0.70 | TAAR1 (0.67) | TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121641-A1 | 2-AMINOOXAZOLINES AS TAAR1 LIGANDS | F. Hoffmann-Roche AG (CH) | 2009-11-25 | — | — | EP | claimed |
| WO-2008098857-A1 | 2-AMINOOXAZOLINES AS TAAR1 LIGANDS | F. HOFFMANN-LA ROCHE AG (CH) | 2008-08-21 | — | — | WO | claimed |