Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 6/20 | 0.56 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.43 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.43 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.43 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.43 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 8/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | CCR6 | P51684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3613597 | 0.88 | GSK3B (0.64) | GSK3BCCNB2CDK1CCNB1RPS6KB1 | |
| SCHEMBL10270178 | 0.85 | GSK3B (0.56) | GSK3BCCNB2CDK1CCNB1RPS6KB1 | |
| SCHEMBL3602835 | 0.84 | GSK3B (0.53) | GSK3BCCNB2CDK1CCNB1RPS6KB1 | |
| SCHEMBL3607564 | 0.82 | GSK3B (0.51) | GSK3BCCNB2CDK1CCNB1RPS6KB1 | |
| SCHEMBL4555186 | 0.82 | DPP4 (0.38) | GSK3BGSK3ACLK4DPP4DPP7 | |
| SCHEMBL12680897 | 0.82 | GSK3B (0.53) | GSK3BCCNB2CDK1CCNB1RPS6KB1 | |
| SCHEMBL12680898 | 0.81 | GSK3B (0.52) | GSK3BCCNB2CDK1CCNB1RPS6KB1 | |
| SCHEMBL10270180 | 0.81 | GSK3B (0.53) | GSK3BCCNB2CDK1CCNB1RPS6KB1 | |
| SCHEMBL3611415 | 0.81 | GSK3B (0.52) | GSK3BCCNB2CDK1CCNB1RPS6KB1 | |
| SCHEMBL10270311 | 0.81 | GSK3B (0.58) | GSK3BCCNB2CDK1CCNB1RPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2137188-B1 | SUBSTITUTED IMIDAZOPYRIMIDINES AND TRIAZOLOPYRIMIDINES | Bayer Pharma AG (DE) | 2012-06-06 | — | — | EP | disclosed |
| EP-2137188-A2 | SUBSTITUTED IMIDAZOPYRIMIDINES AND TRIAZOLOPYRIMIDINES | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-12-30 | — | — | EP | disclosed |
| WO-2008113469-A2 | SUBSTITUTED IMIDAZOPYRIMIDINES AND TRIAZOLOPYRIMIDINES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-09-25 | — | — | WO | disclosed |