Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL232113 | 0.92 | TSHR (0.33) | TSHRTDP1ALDH1A1 | |
| Ether SCHEMBL5147690 | 0.83 | — | — | |
| SCHEMBL31397809 | 0.82 | TSHR (0.36) | TSHR | |
| SCHEMBL12837680 | 0.81 | TSHR (0.40) | TSHRALDH1A1 | |
| SCHEMBL108316 | 0.81 | TSHR (0.40) | TSHRALDH1A1 | |
| SCHEMBL3310241 | 0.81 | TSHR (0.42) | TSHRTDP1ALDH1A1 | |
| SCHEMBL8147282 | 0.81 | TSHR (0.40) | TSHRALDH1A1 | |
| Oxirane SCHEMBL14801898 | 0.80 | — | — | |
| SCHEMBL22456 | 0.80 | TSHR (0.41) | TSHRTDP1ALDH1A1 | |
| SCHEMBL17642229 | 0.76 | TSHR (0.39) | TSHRTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588437-B1 | BRANCHED SECONDARY ALCOHOL ALKOXYLATE SURFACTANTS AND PROCESS TO MAKE THEM | DOW GLOBAL TECHNOLOGIES LLC (US) | 2019-01-02 | — | — | EP | claimed |
| EP-1885760-B1 | CORE/SHELL FLUOROPOLYMER DISPERSIONS WITH LOW FLUOROSURFACTANT CONTENT | DU PONT (US) | 2012-08-01 | — | — | EP | disclosed |
| US-7612139-B2 | high molecular weight polytetrafluoroethylene core and a lower molecular weight polytetrafluoroethylene shell, and small amount 2 to11 weight % of nonionic surfactant polyoxyethylene glycol, contain no aromatic group; environmentally friendly; decomposed at low temeprature; coatings for metal, cookware | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-11-03 | — | — | US | disclosed |
| EP-1885760-A1 | CORE/SHELL FLUOROPOLYMER DISPERSIONS WITH LOW FLUOROSURFACTANT CONTENT | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2008-02-13 | — | — | EP | disclosed |
| WO-2006127317-A1 | CORE/SHELL FLUOROPOLYMER DISPERSIONS WITH LOW FLUOROSURFACTANT CONTENT | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2006-11-30 | — | — | WO | disclosed |
| US-20060264537-A1 | Core/shell fluoropolymer dispersions with low fluorosurfactant content | THE CHEMOURS COMPANY FC, LLC | 2006-11-23 | — | — | US | disclosed |