SCHEMBL4564345

SCHEMBL4564345

CN(C)C(=O)c1c(-c2nnc(C(C)(C)C)o2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 5/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4148726 0.95 CNR2 (0.74) CNR2
SCHEMBL4564029 0.92 CNR2 (0.71) CNR2
SCHEMBL4147056 0.91 CNR2 (0.72) CNR2
SCHEMBL923459 0.91 CNR2 (0.82) CNR2
SCHEMBL4133206 0.91 CNR2 (0.79) CNR2
SCHEMBL4010806 0.90 CNR2 (0.78) CNR2
SCHEMBL4147648 0.88 CNR2 (0.80) CNR2
SCHEMBL4009689 0.87 CNR2 (0.69) CNR2
SCHEMBL4130329 0.87 CNR2 (0.79) CNR2
SCHEMBL923844 0.87 CNR2 (1.00) CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009078498-A1 BIARYLPYRAZOLE 4-CARBOXAMIDES AS CANNABINOID CB1 RECEPTOR LIGANDS GREEN CROSS CORPORATION (KR) 2009-06-25 WO disclosed