Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 19/20 | 0.51 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.50 |
| ▸ | PHGDH | O43175 | 1/20 | 0.44 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL691342 | 1.00 | PTGER4 (0.51) | PTGER4PTGER2PHGDHPTGDR | |
| SCHEMBL3980731 | 0.92 | PTGER4 (0.43) | PTGER4PTGER2 | |
| SCHEMBL3978068 | 0.86 | PTGER4 (0.53) | PTGER4PTGER2PHGDHPTGDR | |
| SCHEMBL3987711 | 0.83 | PTGER4 (0.57) | PTGER4PTGER2PHGDHPTGDR | |
| SCHEMBL27661880 | 0.83 | PTGER4 (0.57) | PTGER4PTGER2PHGDHPTGDR | |
| SCHEMBL692249 | 0.82 | PTGER4 (0.61) | PTGER4PTGER2PHGDHPTGDR | |
| SCHEMBL3978147 | 0.82 | PTGER4 (0.55) | PTGER4PTGER2PHGDHPTGDR | |
| SCHEMBL4564416 | 0.82 | PTGER4 (0.55) | PTGER4PTGER2PHGDHPTGDR | |
| SCHEMBL3986676 | 0.80 | SERPINE1 (0.44) | PTGER2PTGDR | |
| SCHEMBL692553 | 0.79 | PTGER4 (0.64) | PTGER4PTGER2PHGDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090036495-A1 | Combinations Comprising Alpha-2-Delta Ligands and Ep4 Receptor Antagonists | PFIZER, INC. | 2009-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036495-A1 | Combinations Comprising Alpha-2-Delta Ligands and Ep4 Receptor Antagonists | PTGER4, PTGER2, OPRL1 | PTGER4 1/4885PTGER2 2/4885PHGDH 2048/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.