Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.85 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6078570 | 0.92 | F10 (1.00) | F10 | |
| SCHEMBL6078815 | 0.90 | F10 (0.82) | F10 | |
| SCHEMBL4564514 | 0.83 | F10 (0.60) | F10CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6079507 | 0.82 | F10 (0.69) | F10CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6079429 | 0.81 | F10 (0.61) | F10CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6079100 | 0.77 | F10 (0.63) | F10CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6079307 | 0.77 | F10 (0.62) | F10 | |
| SCHEMBL6079421 | 0.76 | F10 (0.73) | F10 | |
| SCHEMBL6078381 | 0.76 | F10 (0.62) | F10 | |
| SCHEMBL6079425 | 0.76 | F10 (0.63) | F10CYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2020411-A1 | SPIRO TETRACYCLIC COMPOUND | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2009-02-04 | — | — | EP | disclosed |