SCHEMBL4564792

SCHEMBL4564792

N#CSCSc1nc2ccccc2s1.O=S(=O)(C(Cl)(Cl)Cl)C(Cl)(Cl)Cl

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.56
CYP2D6 P10635 3/20 0.56
CYP2C19 P33261 3/20 0.56
CYP3A4 P08684 2/20 0.56
MAPK1 P28482 2/20 0.56
L3MBTL1 Q9Y468 2/20 0.56
HIF1A Q16665 1/20 0.56
ALDH1A1 P00352 7/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
KMT2A Q03164 3/20 0.50
MAPT P10636 2/20 0.50
LMNA P02545 1/20 0.50
HTT P42858 1/20 0.50
HSD17B10 Q99714 4/20 0.48
POLB P06746 3/20 0.47
APEX1 P27695 2/20 0.47
RECQL P46063 1/20 0.47
CYP2C9 P11712 1/20 0.45
STAT6 P42226 1/20 0.45
HPGD P15428 4/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29352673 0.87 CYP1A2 (0.73) CYP1A2CYP2D6CYP2C19CYP3A4MAPK1
SCHEMBL8887013 0.87 CYP1A2 (0.73) CYP1A2CYP2D6CYP2C19CYP3A4MAPK1
SCHEMBL54175 0.87 CYP1A2 (0.73) CYP1A2CYP2D6CYP2C19CYP3A4MAPK1
Thiocyanic Acid SCHEMBL8734334 0.83 CYP1A2 (0.67) CYP1A2CYP2D6CYP2C19CYP3A4MAPK1
Urea SCHEMBL28131099 0.83 CYP1A2 (0.61) CYP1A2CYP2D6CYP2C19CYP3A4MAPK1
Dimethylamine SCHEMBL8652976 0.82 CYP1A2 (0.65) CYP1A2CYP2D6CYP2C19CYP3A4MAPK1
2-Mercaptobenzothiazole SCHEMBL8153954 0.80 CYP1A2 (0.61) CYP1A2CYP2D6CYP2C19CYP3A4MAPK1
Glutaral SCHEMBL9224584 0.80 CYP1A2 (0.57) CYP1A2CYP2D6CYP2C19CYP3A4MAPK1
SCHEMBL29729525 0.77 APEX1 (0.51) CYP1A2CYP2D6CYP2C19CYP3A4MAPK1
Di(Hydroxyethyl)Ether SCHEMBL9867190 0.77 CYP1A2 (0.57) CYP1A2CYP2D6CYP2C19CYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1517859-A4 TREATING MICRO-ORGANISMS IN WATER USING BORON CONDITIONED ENZYMES NOVAPHARM RES AUSTRALIA (AU) 2009-06-17 EP disclosed
EP-1517859-A1 TREATING MICRO-ORGANISMS IN WATER USING BORON CONDITIONED ENZYMES NOVAPHARM RESEARCH (AUSTRALIA) PTY. LIMITED (AU) 2005-03-30 EP disclosed
WO-2004002896-A1 TREATING MICRO-ORGANISMS IN WATER USING BORON CONDITIONED ENZYMES NOVAPHARM RESEARCH (AUSTRALIA) PTY LTD (AU) 2004-01-08 WO disclosed