Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.42 |
| ▸ | MEN1 | O00255 | 11/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 7/20 | 0.40 |
| ▸ | MMP13 | P45452 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | ALPG | P10696 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 3/20 | 0.40 |
| ▸ | BLM | P54132 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13707089 | 0.91 | HTT (0.41) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL13172531 | 0.90 | MEN1 (0.46) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL4564926 | 0.89 | MEN1 (0.42) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL4564929 | 0.89 | MEN1 (0.42) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL10987774 | 0.81 | MEN1 (0.61) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL12901136 | 0.79 | MAPT (0.60) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL13292512 | 0.78 | MAPT (0.40) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL4505267 | 0.78 | MEN1 (0.52) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL4499078 | 0.77 | PTPN1 (0.38) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL13292510 | 0.76 | PTPN1 (0.38) | MAPTMEN1KMT2AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592188-B2 | environmentally sensitive fluorescent dye covalently linked to a binding domain which has specific affinity for a target molecule; fluorescence resonance energy transfer; detecting changes in the binding, conformational change; detecting human immunodeficiency virus | THE SCRIPPS RESEARCH INSTITUTE (US) | 2009-09-22 | — | — | US | disclosed |
| US-20060029946-A1 | Live cell biosensors | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-02-09 | — | — | US | disclosed |