SCHEMBL4565025

SCHEMBL4565025

COC(=O)c1cccc(CCN2CCN(c3nc(C)c(C(=O)NCc4ccccc4)s3)C2=O)c1

nearest known ligand 0.68

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SCD O00767 19/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL242539 0.92 SCD (0.78) SCD
SCHEMBL244786 0.89 SCD (0.81) SCD
SCHEMBL243719 0.85 SCD (0.76) SCD
SCHEMBL246305 0.84 SCD (0.82) SCD
SCHEMBL243008 0.81 SCD (1.00) SCD
SCHEMBL241995 0.81 SCD (0.77) SCD
SCHEMBL245140 0.81 SCD (0.83) SCD
SCHEMBL243777 0.80 SCD (0.76) SCD
SCHEMBL1912034 0.79 SCD (0.77) SCD
SCHEMBL242641 0.79 SCD (0.58) SCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2054408-A2 HETEROCYCLIC COMPOUNDS SUITABLE FOR THE TREATMENT OF DISEASES RELATED TO ELEVATED LIPID LEVEL Novartis Ag (CH) 2009-05-06 EP disclosed
WO-2008127349-A2 HETEROCYCLIC COMPOUNDS SUITABLE FOR THE TREATMENT OF DISEASES RELATED TO ELEVATED LIPID LEVEL NOVARTIS AG (CH) 2008-10-23 WO disclosed