Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 20/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4530778 | 0.93 | MC4R (0.88) | MC4R | |
| SCHEMBL4514759 | 0.90 | MC4R (1.00) | MC4R | |
| SCHEMBL4511840 | 0.89 | MC4R (1.00) | MC4R | |
| SCHEMBL4511414 | 0.89 | MC4R (1.00) | MC4R | |
| SCHEMBL4514793 | 0.89 | MC4R (1.00) | MC4R | |
| SCHEMBL4517022 | 0.88 | MC4R (1.00) | MC4R | |
| SCHEMBL4532266 | 0.88 | MC4R (1.00) | MC4R | |
| SCHEMBL4520636 | 0.88 | MC4R (0.86) | MC4R | |
| SCHEMBL4516829 | 0.87 | MC4R (0.82) | MC4R | |
| SCHEMBL4520268 | 0.87 | MC4R (1.00) | MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7560460-B2 | Substituted piperazines and methods of use | AMGEN INC. (US) | 2009-07-14 | — | — | US | claimed |