Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 20/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4565822 | 0.90 | TRPV1 (0.53) | TRPV1 | |
| SCHEMBL15021221 | 0.89 | TRPV1 (0.61) | TRPV1 | |
| SCHEMBL4565369 | 0.88 | TRPV1 (0.60) | TRPV1 | |
| SCHEMBL15021714 | 0.88 | TRPV1 (0.64) | TRPV1 | |
| SCHEMBL15022298 | 0.88 | TRPV1 (0.64) | TRPV1 | |
| SCHEMBL15021626 | 0.88 | TRPV1 (0.64) | TRPV1 | |
| SCHEMBL15021413 | 0.88 | TRPV1 (0.64) | TRPV1 | |
| SCHEMBL15021768 | 0.87 | TRPV1 (0.59) | TRPV1 | |
| SCHEMBL4565894 | 0.82 | TRPV1 (0.54) | TRPV1 | |
| SCHEMBL15021692 | 0.82 | TRPV1 (0.52) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2012778-A2 | ANTAGONISTS OF THE VANILLOID RECEPTOR SUBTYPE 1 (VR1) AND USES THEREOF | Abbott Laboratories (US) | 2009-01-14 | — | — | EP | disclosed |
| WO-2007121299-A2 | ANTAGONISTS OF THE VANILLOID RECEPTOR SUBTYPE 1 (VR1) AND USES THEREOF | ABBOTT LABORATORIES (US) | 2007-10-25 | — | — | WO | disclosed |