Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4125708 | 0.78 | — | — | |
| SCHEMBL4125701 | 0.78 | — | — | |
| SCHEMBL4140290 | 0.62 | — | — | |
| SCHEMBL4142975 | 0.60 | ADORA1 (0.40) | KDM4EMAPTMEN1THRBKMT2A | |
| SCHEMBL4143721 | 0.59 | GRM2 (0.38) | KDM4EMAPTMEN1THRBKMT2A | |
| SCHEMBL4147195 | 0.55 | — | — | |
| SCHEMBL16331703 | 0.54 | GRM2 (0.43) | KDM4EMAPTMEN1THRBKMT2A | |
| SCHEMBL13142993 | 0.54 | KDM4E (0.68) | KDM4EMAPTMEN1THRBKMT2A | |
| SCHEMBL4136463 | 0.53 | GAA (0.30) | MAPTMEN1KMT2A | |
| SCHEMBL17009473 | 0.53 | KDM4E (0.78) | KDM4EMAPTMEN1THRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009032179-A1 | PHOSPHADIAZINE HCV POLYMERASE INHIBITORS III AND VI | IDENIX PHARMACEUTICALS, INC. (US) | 2009-03-12 | — | — | WO | disclosed |