Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.49 |
| ▸ | COMT | P21964 | 8/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8092527 | 0.84 | COMT (0.54) | TYRCOMT | |
| SCHEMBL2117671 | 0.78 | TYR (0.43) | TYRCOMTAPP | |
| SCHEMBL2115662 | 0.74 | TYR (0.47) | TYRCOMTAPPHRH3 | |
| SCHEMBL2606805 | 0.72 | TYR (0.46) | TYRCOMT | |
| SCHEMBL2606789 | 0.69 | COMT (0.37) | TYRCOMTAPPHRH3 | |
| SCHEMBL2606803 | 0.68 | COMT (0.36) | TYRCOMTAPPHRH3 | |
| SCHEMBL11925263 | 0.68 | TYR (0.44) | TYRCOMT | |
| SCHEMBL11926716 | 0.68 | TYR (0.49) | TYRCOMTAPP | |
| SCHEMBL16882309 | 0.68 | TYR (0.72) | TYRCOMT | |
| SCHEMBL11925254 | 0.67 | TYR (0.43) | TYRCOMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2134688-A1 | FLUORINATED DERIVATIVES OF DEFERIPRONE | Apotex Technologies Inc. (CA) | 2009-12-23 | — | — | EP | disclosed |
| WO-2008116301-A1 | FLUORINATED DERIVATIVES OF DEFERIPRONE | APOTEX TECHNOLOGIES INC. (CA) | 2008-10-02 | — | — | WO | disclosed |