Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 20/20 | 0.55 |
| ▸ | HSP90AB1 | P08238 | 20/20 | 0.55 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.49 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL421114 | 0.97 | HSP90AA1 (0.58) | HSP90AA1HSP90AB1HSP90B1TRAP1 | |
| SCHEMBL421216 | 0.95 | HSP90AA1 (0.57) | HSP90AA1HSP90AB1HSP90B1TRAP1 | |
| SCHEMBL3415426 | 0.89 | HSP90AA1 (0.57) | HSP90AA1HSP90AB1HSP90B1TRAP1 | |
| SCHEMBL17099717 | 0.86 | HSP90AA1 (0.59) | HSP90AA1HSP90AB1HSP90B1TRAP1 | |
| SCHEMBL421107 | 0.85 | HSP90AA1 (0.74) | HSP90AA1HSP90AB1HSP90B1TRAP1 | |
| SCHEMBL3417666 | 0.80 | HSP90AB1 (0.58) | HSP90AA1HSP90AB1HSP90B1TRAP1 | |
| SCHEMBL15522262 | 0.80 | HSP90AA1 (0.60) | HSP90AA1HSP90AB1HSP90B1TRAP1 | |
| SCHEMBL3415389 | 0.79 | HSP90AA1 (0.59) | HSP90AA1HSP90AB1HSP90B1TRAP1 | |
| SCHEMBL15525995 | 0.79 | HSP90AA1 (0.58) | HSP90AA1HSP90AB1HSP90B1TRAP1 | |
| SCHEMBL421470 | 0.79 | HSP90AA1 (0.55) | HSP90AA1HSP90AB1HSP90B1TRAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2026797-A2 | METHOD FOR TREATING NON-HODGKIN'S LYMPHOMA | Synta Pharmaceuticals Corporation (US) | 2009-02-25 | — | — | EP | disclosed |
| WO-2007140002-A2 | METHOD FOR TREATING NON-HODGKIN'S LYMPHOMA | SYNTA PHARMACEUTICALS CORP. (US) | 2007-12-06 | — | — | WO | disclosed |