Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | XIAP | P98170 | 5/20 | 0.32 |
| ▸ | BIRC3 | Q13489 | 3/20 | 0.32 |
| ▸ | BIRC2 | Q13490 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4407708 | 0.86 | DPP8 (0.37) | DPP8DPP9DPP4DPP7XIAP | |
| SCHEMBL8239022 | 0.86 | DPP8 (0.37) | DPP8DPP9DPP4DPP7XIAP | |
| SCHEMBL4406606 | 0.85 | XIAP (0.33) | DPP8DPP9XIAPBIRC3 | |
| SCHEMBL4458000 | 0.85 | DPP8 (0.37) | DPP8DPP9DPP4DPP7XIAP | |
| SCHEMBL13594519 | 0.85 | DPP8 (0.37) | DPP8DPP9DPP4DPP7XIAP | |
| SCHEMBL8230244 | 0.83 | HTRA1 (0.37) | DPP8DPP9XIAPBIRC3 | |
| SCHEMBL8230784 | 0.80 | ELANE (0.34) | DPP8DPP9DPP4DPP7XIAP | |
| SCHEMBL8189392 | 0.77 | NAMPT (0.34) | DPP8DPP9 | |
| SCHEMBL8241586 | 0.75 | ELANE (0.40) | DPP8DPP9DPP4DPP7 | |
| SCHEMBL4407737 | 0.75 | ELANE (0.40) | DPP8DPP9DPP4DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029153-A2 | HEPATITIS C SERINE PROTEASE INHIBITORS AND USES THEREFOR | Phenomix Corporation (US) | 2009-03-04 | — | — | EP | disclosed |
| WO-2007089618-A2 | HEPATITIS C SERINE PROTEASE INHIBITORS AND USES THEREFOR | PHENOMIX CORPORATION (US) | 2007-08-09 | — | — | WO | disclosed |