SCHEMBL4566236

SCHEMBL4566236

Cc1c(-c2noc(C3CC=CC3)n2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1

nearest known ligand 0.60

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 2/20 0.53
CNR2 P34972 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4554921 0.93 CNR1 (0.56) CNR1CNR2
SCHEMBL923865 0.91 CNR1 (0.59) CNR1CNR2
SCHEMBL924539 0.91 CNR1 (0.58) CNR1CNR2
SCHEMBL922986 0.90 CNR1 (0.60) CNR1CNR2
SCHEMBL923331 0.90 CNR1 (0.60) CNR1CNR2
SCHEMBL922855 0.87 CNR2 (0.52) CNR1CNR2
SCHEMBL923995 0.84 CNR1 (0.58) CNR1
SCHEMBL922854 0.81 CNR2 (0.67) CNR2
SCHEMBL4462400 0.81 CNR2 (0.67) CNR2
SCHEMBL923058 0.81 CNR1 (0.54) CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2097410-A1 HETEROARYL-PYRAZOLE DERIVATIVES AS CANNABINOID CB1 RECEPTOR ANTAGONISTS Green Cross Corporation (KR) 2009-09-09 EP disclosed
WO-2008039023-A1 HETEROARYL-PYRAZOLE DERIVATIVES AS CANNABINOID CB1 RECEPTOR ANTAGONISTS GREEN CROSS CORPORATION (KR) 2008-04-03 WO disclosed