Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 16/20 | 0.62 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.59 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.48 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4019165 | 1.00 | PTGER4 (0.62) | PTGER4PTGER2GPR139PTGDRPTGER1 | |
| SCHEMBL4012692 | 0.93 | PTGER4 (0.54) | PTGER4PTGER2GPR139PTGER1ALDH1A1 | |
| SCHEMBL13770289 | 0.89 | PTGER4 (0.48) | PTGER4PTGER2GPR139PTGER1ALDH1A1 | |
| SCHEMBL4013897 | 0.87 | PTGER4 (0.67) | PTGER4PTGER2PTGDRALDH1A1 | |
| SCHEMBL27653418 | 0.87 | PTGER4 (0.67) | PTGER4PTGER2PTGDRALDH1A1 | |
| SCHEMBL690993 | 0.84 | PTGER4 (0.67) | PTGER4PTGER2PTGDRPTGER1 | |
| SCHEMBL26914664 | 0.84 | PTGER4 (0.67) | PTGER4PTGER2PTGDRPTGER1 | |
| SCHEMBL692263 | 0.83 | PTGER4 (0.71) | PTGER4PTGER2PTGDR | |
| SCHEMBL691142 | 0.82 | PTGER4 (0.63) | PTGER4PTGER2PTGDRPTGER1 | |
| SCHEMBL691725 | 0.81 | PTGER4 (0.65) | PTGER4PTGER2PTGDRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005102389-A9 | COMBINATIONS COMPRISING ALPHA-2-DELTA LIGANDS AND EP4 RECEPTOR ANTAGONISTS | PFIZER PROD INC (US) | 2009-04-30 | — | — | WO | disclosed |