Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 11/20 | 0.47 |
| ▸ | ACACA | Q13085 | 10/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13590745 | 0.89 | ACACB (0.56) | ACACBACACAKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL4395489 | 0.89 | ACACB (0.52) | ACACBACACAKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL4395481 | 0.89 | ACACB (0.52) | ACACBACACAKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL13590746 | 0.88 | ACACB (0.60) | ACACBACACAKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL13768280 | 0.88 | ACACB (0.53) | ACACBACACAKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL4392817 | 0.85 | ACACB (0.51) | ACACBACACAKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL4392809 | 0.85 | ACACB (0.51) | ACACBACACAKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL4391594 | 0.84 | ACACB (0.54) | ACACBACACAKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL4391583 | 0.84 | ACACB (0.54) | ACACBACACAKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL4395558 | 0.83 | ACACB (0.54) | ACACBACACAKDM4EALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009082346-A1 | NEW ACETYL COENZYME A CARBOXYLASE (ACC) INHIBITORS AND USES IN TREATMENTS OF OBESITY AND DIABETES MELLITUS - 087 | ASTRAZENECA AB (SE) | 2009-07-02 | — | — | WO | claimed |