Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17264246 | 0.81 | CYP4F2 (0.39) | CYP4F2CYP4A11 | |
| SCHEMBL24915578 | 0.81 | CYP4F2 (0.42) | CYP4F2CYP4A11CCR1 | |
| SCHEMBL20462595 | 0.79 | CYP4F2 (0.35) | CYP4F2CYP4A11 | |
| SCHEMBL11915937 | 0.79 | CYP4F2 (0.35) | CYP4F2CYP4A11 | |
| SCHEMBL20462578 | 0.78 | CYP4F2 (0.43) | CYP4F2CYP4A11 | |
| SCHEMBL2455142 | 0.72 | CYP4F2 (0.39) | CYP4F2CYP4A11 | |
| SCHEMBL15556823 | 0.72 | CASR (0.40) | CYP4F2CYP4A11 | |
| SCHEMBL3794461 | 0.71 | — | — | |
| SCHEMBL19497563 | 0.71 | CYP4F2 (0.39) | CYP4F2CYP4A11 | |
| SCHEMBL22693610 | 0.70 | HRH1 (0.35) | CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121638-A2 | NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | Merck & Co., Inc. (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008076225-A2 | NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | MERCK & CO., INC. (US) | 2008-06-26 | — | — | WO | disclosed |
| WO-2008076223-A1 | NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | MERCK & CO., INC. (US) | 2008-06-26 | — | — | WO | disclosed |