Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.52 |
| ▸ | LMNA | P02545 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3240297 | 0.87 | TSHR (0.65) | TSHRALDH1A1LMNAMAPTHTT | |
| SCHEMBL1821090 | 0.84 | TSHR (0.54) | TSHRALDH1A1LMNAMAPTHPGD | |
| SCHEMBL15022885 | 0.84 | TSHR (0.54) | TSHRALDH1A1LMNAMAPTHPGD | |
| SCHEMBL14785027 | 0.82 | TSHR (0.59) | TSHRALDH1A1LMNAMAPTHTT | |
| SCHEMBL16386112 | 0.81 | EPHX1 (0.48) | TSHRALDH1A1LMNAMAPTHPGD | |
| SCHEMBL14060334 | 0.81 | TSHR (0.57) | TSHRALDH1A1LMNAMAPTHPGD | |
| SCHEMBL16386110 | 0.81 | TSHR (0.50) | TSHRALDH1A1LMNAMAPTHPGD | |
| SCHEMBL14873550 | 0.80 | TSHR (0.61) | TSHRALDH1A1LMNAMAPTHTT | |
| SCHEMBL1203949 | 0.80 | CYP2C19 (0.62) | TSHRALDH1A1LMNAMAPTHPGD | |
| SCHEMBL8330289 | 0.80 | CYP1A2 (0.58) | TSHRALDH1A1LMNAMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121637-A1 | ANTHRANILAMIDE INHIBITORS OF AURORA KINASE | Smithkline Beecham Corporation (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008092049-A1 | ANTHRANILAMIDE INHIBITORS OF AURORA KINASE | SMITHKLINE BEECHAM CORPORATION (US) | 2008-07-31 | — | — | WO | disclosed |
| US-4659370-A | Substituted phenoxypropionates and herbicidal compositions containing same and their herbicidal use | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1987-04-21 | — | — | US | disclosed |
| US-4614536-A | Certain pyridyloxy-phenoxy-propionate derivatives, herbicidal compositions containing same and their herbicidal method of use | NIHON TOKUSHU NOYAKU SEIZO, K.K. (JP) | 1986-09-30 | — | — | US | disclosed |
| EP-0092112-B1 | SUBSTITUTED PHENOXY PROPIONATES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1985-03-06 | — | — | EP | disclosed |
| US-4500346-A | Substituted phenoxypropionates and herbicidal compositions containing same and their herbicidal use | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1985-02-19 | — | — | US | disclosed |
| EP-0092112-A1 | Substituted phenoxy propionates | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1983-10-26 | — | — | EP | disclosed |